{"id":955,"date":"2021-09-03T10:54:14","date_gmt":"2021-09-03T09:54:14","guid":{"rendered":"https:\/\/www.sedapds.com\/?p=955"},"modified":"2023-02-16T15:13:12","modified_gmt":"2023-02-16T15:13:12","slug":"sedas-cutting-edge-differential-scanning-calorimetry-capabilities","status":"publish","type":"post","link":"https:\/\/www.sedapds.com\/news\/sedas-cutting-edge-differential-scanning-calorimetry-capabilities\/","title":{"rendered":"Seda\u2019s cutting-edge Differential Scanning Calorimetry capabilities"},"content":{"rendered":"<p><span data-contrast=\"none\">What is the lowest temperature below 0 \u00b0C that a Differential Scanning Calorimetry (DSC) apparatus can achieve? <\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:251}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">This question may sound counter-intuitive at first, and rightly so. The word\u00a0<\/span><i><span data-contrast=\"none\">calorimetry<\/span><\/i><span data-contrast=\"none\">\u00a0is derived from the Latin word\u00a0<\/span><i><span data-contrast=\"none\">calor<\/span><\/i><span data-contrast=\"none\">, meaning heat, warmth and the Greek word\u00a0<\/span><i><span data-contrast=\"none\">metron<\/span><\/i><span data-contrast=\"none\">, meaning measure. Differential Scanning Calorimetry apparatus in fact measures the difference in the amount of heat required to increase the temperature of a sample and a reference. These measurements provide valuable information such as glass transition, crystallization and melting temperatures. Since its inception, Seda\u2019s strong expertise in the thermal analysis field has been at the core of their offering. The acquisition of a top of the range <\/span><a href=\"https:\/\/www.tainstruments.com\/dsc-2500\/\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">DSC 2500<\/span><\/a><span data-contrast=\"none\"> from the world-leading manufacturer TA Instruments was the first step in that direction. Seda\u2019s DSC 2500 has now been used for the successful delivery of a variety of projects spanning from the screening and selection of amorphous solid dispersion systems for poorly soluble APIs to the understanding of complex phase change behaviours.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:251}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">Now, going back to the initial question, it turns out to be a very pertinent one. Seda has now coupled their DSC 2500 with the <\/span><a href=\"https:\/\/www.tainstruments.com\/products\/thermal-analysis\/thermal-analysis-accessories\/differential-scanning-calorimeters-accessories\/\" target=\"_blank\" rel=\"noopener\"><span data-contrast=\"none\">Refrigerated Cooling System 120<\/span><\/a><span data-contrast=\"none\"> (again from TA Instruments) which enables DSC\/modulated DSC operations at temperatures as low as -120 \u00b0C. This powerful combination allows Seda to expand their offering to clients who are looking into understanding, for example, freezing behaviour of their drug products, establishing data-driven storage temperatures, and investigating the impact of variability in cold supply chains.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:251}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">All in all, Seda\u2019s cutting-edge DSC capabilities and expertise will benefit all those clients who want to design and develop more robust drug products, which will ultimately result in better treatments for their patients.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:160,&quot;335559740&quot;:251}\">\u00a0<\/span><\/p>\n<p>Learn more about the <a href=\"https:\/\/www.sedapds.com\/services\/laboratory-services\/\" target=\"_blank\" rel=\"noopener\">laboratory\u00a0services<\/a> we offer here at Seda.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What is the lowest temperature below 0 \u00b0C that a Differential Scanning Calorimetry (DSC) apparatus can achieve? \u00a0 This question may sound counter-intuitive at first, and rightly so. The word\u00a0calorimetry\u00a0is derived from the Latin word\u00a0calor, meaning heat, warmth and the Greek word\u00a0metron, meaning measure. Differential Scanning Calorimetry apparatus in fact measures the difference in the&#8230;<\/p>\n","protected":false},"author":2,"featured_media":973,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0},"categories":[1],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v15.5 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<meta name=\"description\" content=\"Learn more about Seda\u2019s cutting-edge Differential Scanning Calorimetry capabilities with our top of the range DSC 2500 apparatus.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.sedapds.com\/news\/sedas-cutting-edge-differential-scanning-calorimetry-capabilities\/\" \/>\n<meta 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